Saturday, 25 February 2012

Botulism-fatal Paralytic illness

Botulism is a rare and fatal disease paralytic, affecting millions of people around the world. The disease occurs due to a poisonous neurotoxin released by an anaerobic, Spore forming bacterium, known as an (Clostridium botulinum).


There are three different forms of botulism, which include food borne, SCAR and botyliasis. In the United States, approximately 72% of the cases reported is infant formula, 25 percent is food obtained and the rest is botulism.


Symptoms


Displays the symptoms of botulism in adults within 12-48 hours after eating contaminated food. In the case of babies, these symptoms occur within 3-30 days after the recruitment of baktiriakoys. In the case of botulism, symptoms appear within 4-14 days after the injury. The toxin affects the nervous system, blocking the presynaptic release of the neurotransmitter Acetylcholine. As a result, messages from the nerves are not transferred muscles, thereby preventing muscle stimulation. Initial symptoms include blurred vision and drooping eyelids, dry mouth, constipation, blood pupils, abdominal pain and weakened muscles. Death occurs due to paralysis of respiratory muscles, respiratory failure.


Diagnosis


The most common method of diagnosis is through physical examination. However, the symptoms of botulism toxin is usually similar to other diseases such as Guillain-Barre syndrome, stroke, poisoning, specialising in polio myelitis, tick paralysis, Lambert-Eaton syndrome and Myasthenia configuring gravis. As a result, doctors often get confused. Diagnosis of the disease is through recognition of botulinum in the blood. Stool examinations help detect the presence of bacteria and spores which are excreted via the faeces. In the case of botulism wound exudates, as samples for laboratory tests.

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